Gómez-Gonzalo Marta
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Research scientist
c/o Complesso Biologico Interdipartimentale
A. Vallisneri
Viale Giuseppe Colombo 3
Padova 35131
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My research in the field of Neuroscience focuses on the role of the bi-directional communication between neurons and astrocytes in brain function. The close cooperation between these two cell populations finely shapes the activity of neuronal circuits under physiological conditions and also contributes to brain disorders, including epilepsy and Alzheimer's disease. Using an electrophysiological approach in brain slices, combined with calcium imaging techniques, adeno-associated viral tools and behavioral tests, the current goal of my research is to study how astrocyte activity influences the circuit of the ventral tegmental area, a dopaminergic region involved in the brain mechanisms of reward, aversion, motivation, addiction and depression. The ultimate goal of this study is to determine how, under stress conditions, astrocyte activity contributes to behavior driven by this dopaminergic region. Recently, I have also begun focusing on the role of astrocytes in neuro-oncological mechanisms.
Representative publications
Gómez-Gonzalo M. (2025) Int.J.Mol.Sci., doi: 10.3390/ijms26062774. “Astrocytes in Rodent Anxiety-Related Behavior: Role of Calcium and Beyond”
Speggiorin M, Chiavegato A, Zonta M, Gómez-Gonzalo M (2024) Cells, doi: 10.3390/cells14010024. “Characterization of the Astrocyte Calcium Response to Norepinephrine in the Ventral Tegmental Area”
Requie LM*, Gómez-Gonzalo M*, Speggiorin M*, Managò F, Melone M, Congiu M, Chiavegato A, Lia A, Zonta M, Losi G, Henriques VJ, Pugliese A, Pacinelli G, Marsicano G, Papaleo F, Muntoni AL, Conti F, Carmignoto G. (2022) Nature Neurosci., doi: 10.1038/s41593-022-01193-4. “Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons.”
Henriques VJ, Chiavegato A, Carmignoto G*, Gómez-Gonzalo M*. (2022) Cells, doi: 10.3390/cells11091400. “Astrocytes Modulate Somatostatin Interneuron Signaling in the Visual Cortex”
Lia A, Henriques VJ, Zonta M, Chiavegato A, Carmignoto G, Gómez-Gonzalo M*, Losi G*. (2021) Front. Cell. Neurosci., doi: 10.3389/fncel.2021.673433. “Calcium Signals in Astrocyte Microdomains, a Decade of Great Advances”
* These authors contributed equally to this work
https://scholar.google.com/citations?user=-7wIu-4AAAAJ&hl=it