Senior research scientist
Parma research unit
via Volturno 39/E
The main goal of the laboratory is to exploit human intracranial recordings to obtain, integrating high spatial and temporal resolution, a four-dimensional representation of the cortical activity capable to render the spatio-temporal dynamics underlying cognitive and perceptual processes.
A specific attention is paid to the sensori-motor integration, and to the characterization of the neural activations shared by both action execution and action observation. These mirror mechanisms can be functionally described thanks to the possibility not only to identify the cortical regions responsive during an ecological task, but also to highlight how each region behaves in time.
Finally, thanks to the unprecedented spatiotemporal resolution characterizing stereo-electroencephalography recordings, we aim at bridging the gap between non-invasive recordings and the human brain, by co-registering stereo-EEG signal with EEG and fMRI signals. In this way, the task-induced modulations observed on non-invasive signals could be associated to a precise spatio-temporal description of the cortical generators activity, and consequently to a clearer explanation of their functional role.
Angelini M, Fabbri-Destro M, Lopomo NF, Gobbo M, Rizzolatti G, Avanzini P., Perspective-dependent reactivity of sensorimotor mu rhythm in alpha and beta ranges during action observation: an EEG study, Sci Rep. 2018 Aug 20;8(1):12429.
Avanzini P, Pelliccia V, Lo Russo G, Orban GA, Rizzolatti G., Multiple time courses of somatosensory responses in human cortex, Neuroimage. 2018 Apr 1;169:212-226.
Dalla Volta R, Avanzini P, De Marco D, Gentilucci M, Fabbri-Destro M., From meaning to categorization: The hierarchical recruitment of brain circuits selective for action verbs, Cortex. 2018 Mar;100:95-110.
Avanzini P, Abdollahi RO, Sartori I, Caruana F, Pelliccia V, Casaceli G, Mai R, Lo Russo G, Rizzolatti G, Orban GA., Four-dimensional maps of the human somatosensory system, Proc Natl Acad Sci U S A. 2016 Mar 29;113(13): E1936-43.
Meletti S, Vaudano AE, Tassi L, Caruana F, Avanzini P., Intracranial time-frequency correlates of seizure-related negative BOLD response in the sensory-motor network, Clin Neurophysiol. 2015 Apr;126(4):847-9.