Mission
The Institute of Neuroscience of the National Research Council (CNR) advances knowledge of the nervous system across the lifespan through excellence in basic, translational, clinical, and population-based research. Its mission is to generate fundamental discoveries, transform them into innovative diagnostic and therapeutic strategies, and contribute to improving human health and quality of life.
The Institute investigates the molecular, cellular, circuit, and systems mechanisms that govern the development, function, plasticity, and aging of the nervous system in health and disease. By studying the central and peripheral nervous systems as dynamic and adaptive biological systems, it seeks to understand how genetic, environmental, and experiential factors interact to shape neural function, behavior, cognition, and resilience throughout life.
A major focus of the Institute is the elucidation of the mechanisms underlying neurodevelopmental disorders, neurological and neurodegenerative diseases, neuromuscular disorders, and brain tumors, with the goal of identifying new opportunities for prevention, diagnosis, and treatment. The Institute also investigates the determinants of healthy aging and brain health at the population level through advanced epidemiological and statistical approaches.
Through the integration of experimental and theoretical disciplines—including molecular and cellular neuroscience, physiology, systems and computational neuroscience, translational medicine, neuro-oncology, and epidemiology—the Institute aims to:
- uncover the fundamental principles governing the organization, function, and plasticity of neural circuits;
- elucidate the biological mechanisms that drive disorders of the nervous and neuromuscular systems and brain tumors;
- identify biomarkers and develop innovative tools for early diagnosis, disease monitoring, and therapeutic intervention;
- advance the understanding of the determinants of health, disease susceptibility, and healthy aging;
- accelerate the translation of scientific discoveries into clinical practice, public health strategies, and evidence-based policies.
Emphasis is placed on understanding the reciprocal interactions between the nervous system and other organs and biological systems, as well as the neural basis of cognition, perception, emotion, and behavior.
As a leading national and international center for neuroscience, the Institute fosters interdisciplinary collaboration, technological innovation, and the training of the next generation of scientists. By connecting fundamental discovery with clinical and societal needs, it serves as a catalyst for scientific progress and a resource for patients, healthcare professionals, policymakers, and the broader community.